Better Informed Decisions

Disease Profiling - Fundamental to any discovery and development program is a solid understanding of the biology underlying the disease state such as:

• Disease-specific profiling of signaling within defined cell populations and subsets
• Identification of new targets
• Identification of cell–cell interactions relevant to disease and treatment effects
• Identification of subtypes of disease to guide early-stage drug development and patient selection in clinical trials

Drug Profiling - Facilitate rational development of therapeutic agents, including small molecules and biologics:

• Uncover on-target and off-target mechanisms of action
• Compare targeting, potency and selectivity of drugs
• Creation of a rational basis for combination therapy to optimize efficacy and minimize undesirable drug interactions

Clinical Development - Enhance the chances for clinical and market success:

• Enablement of rational combination therapies
• PD markers in whole blood
• Clinical trial design directed by defined patient groups
• Facilitate competitive differentiation
• Companion diagnostics

Life Cycle Management - Achieve additional benefits after a drug has reached the market:

• Biological basis for competitive positioning
• Drug expansion and repurposing
• Diagnostic and monitoring tests

Solutions for drug developers across disease areas

Nodality’s scientific and informatics teams have expertise in achieving solutions across a variety of disease areas, including oncology, autoimmune and inflammatory diseases. By applying SCNP™, Nodality offers broad sets of capabilities within each therapeutic area that addresses BioPharma challenges in Oncology, Immunology and other areas.