MANAGEMENT TEAM
 David R. Parkinson, M.D.
President and Chief Executive Officer
Member of the Board of Directors
David R. Parkinson is President and CEO of Nodality, a South San Francisco-based biotechnology company focused on the biological characterization of signaling pathways in patients with malignancy to enable more effective therapeutics development and decision-making. Until October 2007 Dr. Parkinson was Senior Vice President, Oncology Research and Development at Biogen Idec. At Biogen Idec he oversaw all oncology discovery research efforts and the development of the oncology pipeline. Previously he had served as Vice President, Oncology Development, at Amgen and Vice President, Global Clinical Oncology Development at Novartis. During his tenures at Amgen and Novartis, Dr. Parkinson was responsible for clinical development activities leading to a series of successful global drug registrations for important cancer therapeutics, including Gleevec, Femara, Zometa, Kepivance, and Vectibix.
Dr. Parkinson worked at the National Cancer Institute from 1990 to 1997, serving as Chief of the Investigational Drug Branch, then as Acting Associate Director of the Cancer Therapy Evaluation Program, before leaving for Novartis. He has also held academic positions at the M.D. Anderson Cancer Center, University of Texas and New England Medical Center of Tufts University School of Medicine.
He received his M.D. as gold medalist from the University of Toronto Faculty of Medicine in 1977, with Internal Medicine and Hematology/Oncology training in Montreal at McGill University and in Boston at New England Medical Center. Dr. Parkinson is a past Chairman of the Food & Drug Administration (FDA) Biologics Advisory Committee and is a recipient of the FDA's Cody Medal. He is a past President of the International Society of Biological Therapy, and past Editor of the Journal of Immunotherapy. He currently serves on the National Cancer Policy Forum of the Institute of Medicine and is a member of the FDA's Science Board. He was recently elected to the Board of Directors of the American Association of Cancer Research, and continues to serve as Chairman of the AACR Finance Committee.
 David C. Spellmeyer, Ph.D.
Chief Technology Officer and Chief Informatics Officer
Dr. Spellmeyer joined Nodality in September of 2006. Prior to Nodality, he held positions as a research staff member in the IBM Almaden Services Research group, as chief scientific officer and vice president of drug discovery at Signature BioSciences, as executive director at DuPont Pharmaceuticals, as vice president at CombiChem, and a principal scientist at Chiron. Dr. Spellmeyer received his Ph.D. in 1987 from UCLA, and completed his post-doctoral work in pharmaceutical chemistry at UCSF. He continues his interaction with the UCSF research groups through his adjunct assistant professorship. He has authored more than 35 scientific publications and two modeling packages, and frequently makes presentations at scientific seminars.
 James V. Agnello
Chief Financial Officer
Jim Agnello joined the company in December 2008 as Chief Financial Officer. Prior to Nodality he held positions as Senior Vice President and Chief Financial Officer for Clarient, Inc.(NASDAQ:CLRT), a rapidly growing cancer diagnostics company, and as Vice President and Chief Financial Officer for the Motion Systems and Marine Divisions and Chief Accounting Officer for Teleflex Inc. (NYSE:TFX), a large multi-national manufacturing company. Mr. Agnello has over 17 years of experience leading finance teams in diagnostic companies, including 14 years in various senior finance positions with SmithKline Beecham (now GlaxoSmith Kline)'s clinical laboratory sector prior to its merger with Quest Diagnostics. He is a CPA, formerly with Deloitte and Touche, and has a B.A. degree from Rutgers, the State University of New Jersey, and a Masters degree from the Wharton School of Business at the University of Pennsylvania.
 Phil McGarrigle
General Counsel and Chief IP Officer
Phil McGarrigle joined Nodality in February 2008 as General Counsel and Chief IP Officer. Prior to Nodality, he was employed at Affymetrix from 1998 to 2008 and held the position of VP and Chief IP Counsel. Prior to Affymetrix, he was employed at Cetus and then Chiron after the two corporations were merged. He also worked at Chevron Corporation and Kaiser Aluminum and Chemical. Mr. McGarrigle has been an adjunct professor at Santa Clara School of Law from 2000 to the present. He obtained a B.A. degree from the University of New Hampshire and a J.D. from the University of Santa Clara Law School.
 Alessandra Cesano, M.D., Ph.D.
Chief Medical Officer
Alessandra Cesano joined Nodality in March 2008 as Chief Medical Officer. From 2006 until joining Nodality she was at Biogen Idec as Vice President and Medical Officer, Oncology Medical Research. Alessandra has over 15 years experience within the biotech / pharmaceutical industry concentrating in oncology pre-clinical research at The Wistar Institute (Philadelphia, PA), clinical development at both SmithKline Beecham Pharmaceuticals (Collegeville, PA) and Amgen Inc. Along her career path, Alessandra has authored over 85 articles for research publications and is co-inventor in five patents. Additionally, Alessandra, a board certified medical oncologist, holds a PhD in tumor Immunology and a visiting professor and adjunct assistant professor status for the University of Turin (Turin Italy) and University of Pennsylvania (Philadelphia, PA) respectively. Alessandra is fluent in Italian, French, and English.
INVESTORS
Kleiner Perkins Caufield & Byers
Kleiner Perkins Caufield & Byers (KPCB) is an active venture capital partnership headquartered in the San Francisco Bay Area with a large capital base for investment. Since 1972, KPCB has invested in over 400 technology companies which have accrued market valuations exceeding $164 billion, achieved combined revenues of over $81 billion, and created over 279,000 jobs. In this process, KPCB has been privileged to work with some of America's most outstanding entrepreneurs, Chief Executive Officers, and management teams.
Maverick Capital
Since their founding in Dallas in 1993, Maverick has been dedicated to the preservation and growth of its investors’ capital. Today the team of 162 is based in Dallas and New York, conducts research and trading activities in London and has research offices in Baltimore, Philadelphia, San Francisco, Shanghai and Taipei. They have been registered with the Securities and Exchange Commission since 1994, the Commodities Futures Trading Commission since 2000, and the Financial Services Administration since 2006. They are owned by fourteen partners, all current or past participants in their business. Lee S. Ainslie III, who joined the firm at its inception, has served as the sole Portfolio Manager since March of 1995.
Maverick manages private investment funds offering six investment profiles, certain separately managed client accounts and a fund-of-funds (Maverick Stable). Their assets under management totaled $11.3 billion as of March 31, 2008 (all figures herein are updated through this date unless otherwise indicated). Collectively, their partners, employees and related entities are their largest investors, accounting for 21% of their managed assets and confirming the alignment of their interests with those of their investors.
TPG Biotechnology
TPG is a private equity investment firm founded by David Bonderman, James G. Coulter, and William S. Price, III in 1993. The principals of TPG, with affiliated partnerships, have aggregate committed capital of more than $50 billion. TPG’s diverse holdings include Quintiles Transnational, Biomet, IASIS, Neiman Marcus, Burger King and Harrah’s. Founded in 2001, TPG Biotechnology has a total of $1B devoted to investments in information technology and the life sciences in the United States.
BOARD OF DIRECTORS
Risa Stack, Ph.D.
Chair and Member of the Board of Directors
Partner, Kleiner Perkins Caufield & Byers
Dr. Stack joined Kleiner Perkins Caufield & Byers in 2003. Dr. Stack specializes in the development of life science companies. She was the founding CEO and is currently a board member of several companies including CardioDx, Nodality, and an incubation in the personalized medicine area. She is currently on the Board of Directors of Corthera and Trius and a board observer at Codon Devices, Xdx, Orexigen (OREX), Tethys and Pacific Biosciences.
Prior to joining KPCB, Dr. Stack was a Principal at J.P. Morgan Partners in the life science practice for 6 years. While at J.P. Morgan Partners she sponsored a series of investments including Acurian, AlgoRx (now Anesiva), Connetics, Diatide, Ilex Oncology, Illumina, Praecis Pharmaceuticals and Triangle Pharmaceuticals.
Prior to working in the venture capital industry, Dr. Stack worked as a Derivative Specialist on the Chicago Board of Trade where she traded futures and options on government securities. As an intern at ARCH Development Corporation she participated in the development of several companies based on the research of University of Chicago scientists. At Abbott Laboratories, she worked to develop a new Hepatitis C assay system and researched new procedures for evaluating patient samples for HIV and Hepatitis B. Dr. Stack received her B.S. in Genetics and Development with distinction from the University of Illinois and her Ph.D. in Immunology from the University of Chicago. She was also a member of the second class of Kauffman Fellows. Dr. Stack was named as one of the 100 Most Influential Women in Business by the San Francisco Business Times in 2004.
Fred Cohen, M.D., Ph.D.
Member of the Board of Directors
Partner and Managing Director, TPG Biotechnology
Dr. Cohen is a partner at TPG, where he initiated their investment efforts in the life sciences forming TPG Biotechnology. He also retains a position as a Professor of Cellular and Molecular Pharmacology at the University of California, San Francisco. He also serves as a member of the boards of GenomicHealth, XDx, CardioDx, Axcan, Quintiles Transnational, Five Prime Therapeutics, and Matrix Laboratories. He received his M.D. from Stanford, his D.Phil. in Molecular Biophysics from Oxford as a Rhodes Scholar and his Bachelor’s degree from Yale University in Molecular Biophysics and Biochemistry. Dr. Cohen has been a member of the faculty of UCSF since 1986 and is best known for his work on protein structure and the conformational basis of prion disease. He is a member of the Institute of Medicine of the National Academy of Arts and Sciences, and the American Academy of Arts & Sciences
Garry P. Nolan, Ph.D.
Co-Founder
Member of the Board of Directors
Chair of the Scientific Advisory Board
Professor of Microbiology and Immunology, Stanford University School of Medicine
Director of the Stanford NHLBI Proteomics Center
Dr. Nolan received his Ph.D from the Department of Genetics at Stanford at the Herzenberg laboratory, and his B.S. in Genetics from Cornell University, and was a postdoctoral fellow in the laboratory of Dr. David Baltimore at MIT and Rockefeller University. He is the author of over 120 peer-reviewed papers and holds numerous issued patents. He is the recipient of several prestigious awards, and was recently honored as one of the top 25 inventors at Stanford University. He was a Hume Faculty Scholar (1993-98), Trustee of the Leukemia Society of America (1995-98), Burroughs Welcome Fund New Investigator Awardee (1996-2000), HHMI Junior Faculty Scholar Awardee, Leukemia and Lymphoma Society Stohlman Scholar (2000), among others. He is the co-founder of 3 companies, including publicly traded RIGEL (NASDAQ:RIGL).
David R. Parkinson, M.D.
President and Chief Executive Officer
Member of the Board of Directors
David R. Parkinson is President and CEO of Nodality, a South San Francisco-based biotechnology company focused on the biological characterization of signaling pathways in patients with malignancy to enable more effective therapeutics development and decision-making. Until October 2007 Dr. Parkinson was Senior Vice President, Oncology Research and Development at Biogen Idec. At Biogen Idec he oversaw all oncology discovery research efforts and the development of the oncology pipeline. Previously he had served as Vice President, Oncology Development, at Amgen and Vice President, Global Clinical Oncology Development at Novartis. During his tenures at Amgen and Novartis, Dr. Parkinson was responsible for clinical development activities leading to a series of successful global drug registrations for important cancer therapeutics, including Gleevec, Femara, Zometa, Kepivance, and Vectibix.
Dr. Parkinson worked at the National Cancer Institute from 1990 to 1997, serving as Chief of the Investigational Drug Branch, then as Acting Associate Director of the Cancer Therapy Evaluation Program, before leaving for Novartis. He has also held academic positions at the M.D. Anderson Cancer Center, University of Texas and New England Medical Center of Tufts University School of Medicine.
He received his M.D. as gold medalist from the University of Toronto Faculty of Medicine in 1977, with Internal Medicine and Hematology/Oncology training in Montreal at McGill University and in Boston at New England Medical Center. Dr. Parkinson is a past Chairman of the Food & Drug Administration (FDA) Biologics Advisory Committee and is a recipient of the FDA's Cody Medal. He is a past President of the International Society of Biological Therapy, and past Editor of the Journal of Immunotherapy. He currently serves on the National Cancer Policy Forum of the Institute of Medicine and is a member of the FDA's Science Board. He was recently elected to the Board of Directors of the American Association of Cancer Research, and continues to serve as Chairman of the AACR Finance Committee.
David B. Singer
Limited Partner
Maverick Capital
Mr. Singer is responsible for Maverick’s Private Equity and Venture Capital Investments. He joined Maverick in 2004 from Oscient Pharmaceutical Corporation, where he was Chairman of the Board. Mr. Singer is a founder and former CEO of three biotech companies: Affymetrix, Inc., Corcept Therapeutics, Inc., and Genesoft Pharmaceuticals, Oscient’s predecessor. Before these experiences, Mr. Singer was the senior financial officer at Affymax and Heartport. He began his career at Baxter International and worked at Goldman Sachs & Co. Mr. Singer received his B.A. from Yale University and his M.B.A. from Stanford University. He is a Crown Fellow of the Aspen Institute, a Sterling Fellow of Yale University and on the Rand Corporation’s Health Advisory Board. Mr. Singer currently serves on the boards of several private companies.
Russell W. Bradley
Member of the Board of Directors
Vice President Strategic Planning and Business Development, Luminex Corporation
Mr. Bradley joined the Board of Directors of Nodality in September of 2008. Mr. Bradley has over twenty years of international industry experience in both the Life Science and Clinical Diagnostic Testing markets. He is currently Vice President of Strategic Planning and Business Development at Luminex Corporation, a leading provider of biomedical testing technologies. Prior to joining Luminex Corporation in May 2005, Mr. Bradley spent much of his career at Beckman Coulter Corporation where he served in numerous roles of increasing responsibility in the Cellular Analysis Division finally serving as the Director of the Beckman Coulter CARES initiative. During his tenure at Beckman Coulter, Mr. Bradley was involved in the evaluation, market assessment and successful commercial launch of multiple life science technologies and applications. Mr. Bradley obtained a B.Sc. in Immunology and Biochemistry from Monash University, Melbourne, Australia.
Andrew Allen, M.D., Ph.D.
Member of the Board of Directors
Dr Allen joins the board of Nodality having most recently been Chief Medical Officer and EVP at Pharmion Corp, a young cancer therapeutics company acquired by Celgene for $2.9B in 2Q08. Pharmion was the leading company in the fast-growing field of epigenetic therapy, and was the first to show that epigenetic therapy, in the form of Vidaza, a DNA methylation inhibitor, could substantially extend survival in patients with higher-risk myelodysplastic syndromes. Pharmion also secured the approval in Europe of thalidomide for the front-line treatment of multiple myeloma patients ineligible for transplant.
Prior to Pharmion, Dr Allen was Vice President Oncology Drug Development at Chiron, one of the original biotechnology companies in the Bay Area, which was acquired by Novartis in 2006. At Chiron, Dr Allen's team initiated clinical development of three early-stage oncology drugs, both small molecules and biologics, and worked extensively to apply biomarkers and diagnostics to the process of early drug development. His team also collaborated closely with academia, and pioneered a clinical partnership with the Multiple Myeloma Research Consortium. Previously, Dr. Allen served as global project head in Abbott Laboratories' oncology franchise, and prior to that he progressed through positions of increasing responsibility at McKinsey & Company, in the development and execution of business strategies for top-tier biotechnology and pharmaceutical companies, with a focus on oncology.
Dr. Allen qualified in Medicine at Oxford University and earned his Ph.D. from the Imperial College of Science, Technology and Medicine in London. Dr. Allen also obtained post-graduate internal medicine qualification as a Member of Royal College of Physicians (MRCP).
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